Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance

BACKGROUND: Drug resistance is a common cause of treatment failure in cancer patients and encompasses a multitude of different mechanisms. The aim of the present study was to identify drugs effective on multidrug resistant cells. METHODS: The RPMI 8226 myeloma cell line and its multidrug resistant s...

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Détails bibliographiques
Auteurs principaux: Fryknäs, Mårten, Gullbo, Joachim, Wang, Xin, Rickardson, Linda, Jarvius, Malin, Wickström, Malin, Hassan, Saadia, Andersson, Claes, Gustafsson, Mats, Westman, Gunnar, Nygren, Peter, Linder, Stig, Larsson, Rolf
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751689/
https://ncbi.nlm.nih.gov/pubmed/23919498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-374
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