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Transdifferentiation of pancreatic cells by loss of contact-mediated signaling

BACKGROUND: Replacement of dysfunctional β-cells in the islets of Langerhans by transdifferentiation of pancreatic acinar cells has been proposed as a regenerative therapy for diabetes. Adult acinar cells spontaneously revert to a multipotent state upon tissue dissociation in vitro and can be stimul...

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Detaylı Bibliyografya
Asıl Yazarlar: Back, Walter de, Zimm, Roland, Brusch, Lutz
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751562/
https://ncbi.nlm.nih.gov/pubmed/23938152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-77
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