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Transdifferentiation of tadpole pancreatic acinar cells to duct cells mediated by Notch and stromelysin-3
The tadpole pancreas has differentiated acinar cells but an underdeveloped ductal system. At the climax of metamorphosis thyroid hormone (TH) induces the tadpole acinar cells to dedifferentiate to a progenitor state. After metamorphosis is complete the exocrine pancreas redifferentiates in the growi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3394455/ https://ncbi.nlm.nih.gov/pubmed/21194527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.12.020 |
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