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Transdifferentiation of pancreatic cells by loss of contact-mediated signaling
BACKGROUND: Replacement of dysfunctional β-cells in the islets of Langerhans by transdifferentiation of pancreatic acinar cells has been proposed as a regenerative therapy for diabetes. Adult acinar cells spontaneously revert to a multipotent state upon tissue dissociation in vitro and can be stimul...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3751562/ https://ncbi.nlm.nih.gov/pubmed/23938152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-77 |
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