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Effects of KGF on Alveolar Epithelial Cell Transdifferentiation Are Mediated by JNK Signaling

Rat alveolar epithelial cells (AEC) in primary culture transdifferentiate from a type II (AT2) toward a type I (AT1) cell-like phenotype, a process that can be both prevented and reversed by keratinocyte growth factor (KGF). Microarray analysis revealed that these effects of KGF are associated with...

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Detalhes bibliográficos
Main Authors: Qiao, Renli, Yan, Weihong, Clavijo, Carlos, Mehrian-Shai, Ruty, Zhong, Qian, Kim, Kwang-Jin, Ann, David, Crandall, Edward D., Borok, Zea
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214671/
https://ncbi.nlm.nih.gov/pubmed/17872496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0172OC
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