Effects of Phosphorylation on the Structure and Backbone Dynamics of the Intrinsically Disordered Connexin43 C-terminal Domain

Phosphorylation of the connexin43 C-terminal (Cx43CT) domain regulates gap junction intercellular communication. However, an understanding of the mechanisms by which phosphorylation exerts its effects is lacking. Here, we test the hypothesis that phosphorylation regulates Cx43 gap junction intercell...

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Bibliografische gegevens
Hoofdauteurs: Grosely, Rosslyn, Kopanic, Jennifer L., Nabors, Sarah, Kieken, Fabien, Spagnol, Gaëlle, Al-Mugotir, Mona, Zach, Sydney, Sorgen, Paul L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2013
Onderwerpen:
Protein Structure and Folding
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750180/
https://ncbi.nlm.nih.gov/pubmed/23828237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.454389
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