Effects of Phosphorylation on the Structure and Backbone Dynamics of the Intrinsically Disordered Connexin43 C-terminal Domain

Phosphorylation of the connexin43 C-terminal (Cx43CT) domain regulates gap junction intercellular communication. However, an understanding of the mechanisms by which phosphorylation exerts its effects is lacking. Here, we test the hypothesis that phosphorylation regulates Cx43 gap junction intercell...

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Bibliografiske detaljer
Main Authors: Grosely, Rosslyn, Kopanic, Jennifer L., Nabors, Sarah, Kieken, Fabien, Spagnol, Gaëlle, Al-Mugotir, Mona, Zach, Sydney, Sorgen, Paul L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750180/
https://ncbi.nlm.nih.gov/pubmed/23828237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.454389
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