Structural Studies of the Nedd4 WW Domains and Their Selectivity for the Connexin43 (Cx43) Carboxyl Terminus

Neuronal precursor cell-expressed developmentally down-regulated 4 (Nedd4) was the first ubiquitin protein ligase identified to interact with connexin43 (Cx43), and its suppressed expression results in accumulation of gap junction plaques at the plasma membrane. Nedd4-mediated ubiquitination of Cx43...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Spagnol, Gaelle, Kieken, Fabien, Kopanic, Jennifer L., Li, Hanjun, Zach, Sydney, Stauch, Kelly L., Grosely, Rosslyn, Sorgen, Paul L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2016
Onderwerpen:
Protein Structure and Folding
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817190/
https://ncbi.nlm.nih.gov/pubmed/26841867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.701417
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