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Parameter estimation in systems biology models using spline approximation

BACKGROUND: Mathematical models for revealing the dynamics and interactions properties of biological systems play an important role in computational systems biology. The inference of model parameter values from time-course data can be considered as a "reverse engineering" process and is st...

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Autors principals: Zhan, Choujun, Yeung, Lam F
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750107/
https://ncbi.nlm.nih.gov/pubmed/21255466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-14
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