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A New Class of Rhomboid Protease Inhibitors Discovered by Activity-Based Fluorescence Polarization
Rhomboids are intramembrane serine proteases that play diverse biological roles, including some that are of potential therapeutical relevance. Up to date, rhomboid inhibitor assays are based on protein substrate cleavage. Although rhomboids have an overlapping substrate specificity, substrates canno...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3750051/ https://ncbi.nlm.nih.gov/pubmed/23991088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072307 |
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