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Enrichment of processed pseudogene transcripts in L1-ribonucleoprotein particles

Long INterspersed Elements (LINE-1s, L1s) are responsible for over one million retrotransposon insertions and 8000 processed pseudogenes (PPs) in the human genome. An active L1 encodes two proteins (ORF1p and ORF2p) that bind with L1 RNA and form L1-ribonucleoprotein particles (RNPs). Although it is...

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Bibliografiske detaljer
Main Authors: Mandal, Prabhat K., Ewing, Adam D., Hancks, Dustin C., Kazazian, Haig H.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749862/
https://ncbi.nlm.nih.gov/pubmed/23696454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt225
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