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Enrichment of processed pseudogene transcripts in L1-ribonucleoprotein particles

Long INterspersed Elements (LINE-1s, L1s) are responsible for over one million retrotransposon insertions and 8000 processed pseudogenes (PPs) in the human genome. An active L1 encodes two proteins (ORF1p and ORF2p) that bind with L1 RNA and form L1-ribonucleoprotein particles (RNPs). Although it is...

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Main Authors: Mandal, Prabhat K., Ewing, Adam D., Hancks, Dustin C., Kazazian, Haig H.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749862/
https://ncbi.nlm.nih.gov/pubmed/23696454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt225
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