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Spatially-Directed Protein Identification from Tissue Sections by Top-Down LC-MS/MS with Electron Transfer Dissociation

MALDI imaging mass spectrometry (MALDI-IMS) has become a powerful tool for localizing both small molecules and intact proteins in a wide variety of tissue samples in both normal and diseased states. Identification of imaged signals in MALDI-IMS remains a bottleneck in the analysis and limits the int...

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Detalles Bibliográficos
Main Authors: Schey, Kevin L., Anderson, David M., Rose, Kristie L.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749783/
https://ncbi.nlm.nih.gov/pubmed/23718750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac400832w
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