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E-selectin liposomal and nanotube-targeted delivery of doxorubicin to circulating tumor cells

The presence of circulating tumor cells (CTCs) is believed to lead to the formation of secondary tumors via an adhesion cascade involving interaction between adhesion receptors of endothelial cells and ligands on CTCs. Many CTCs express sialylated carbohydrate ligands on their surfaces that adhere t...

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Autori principali: Mitchell, Michael J., Chen, Christina S., Ponmudi, Varun, Hughes, Andrew D., King, Michael R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749772/
https://ncbi.nlm.nih.gov/pubmed/22421423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.02.018
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