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E-selectin liposomal and nanotube-targeted delivery of doxorubicin to circulating tumor cells

The presence of circulating tumor cells (CTCs) is believed to lead to the formation of secondary tumors via an adhesion cascade involving interaction between adhesion receptors of endothelial cells and ligands on CTCs. Many CTCs express sialylated carbohydrate ligands on their surfaces that adhere t...

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Detalhes bibliográficos
Main Authors: Mitchell, Michael J., Chen, Christina S., Ponmudi, Varun, Hughes, Andrew D., King, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749772/
https://ncbi.nlm.nih.gov/pubmed/22421423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.02.018
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