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Liposomal delivery of doxorubicin to hepatocytes in vivo by targeting heparan sulfate

Previous work demonstrated that liposomes, containing an amino acid sequence that binds to hepatic heparan sulfate glycosaminoglycan, show effective targeting to liver hepatocytes. These liposomes were tested to determine whether they can deliver doxorubicin selectively to liver and hepatocytes in v...

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Bibliographic Details
Main Authors: Longmuir, Kenneth J., Haynes, Sherry M., Baratta, Janie L., Kasabwalla, Natasha, Robertson, Richard T.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784200/
https://ncbi.nlm.nih.gov/pubmed/19664697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2009.07.030
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