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E-selectin liposomal and nanotube-targeted delivery of doxorubicin to circulating tumor cells

The presence of circulating tumor cells (CTCs) is believed to lead to the formation of secondary tumors via an adhesion cascade involving interaction between adhesion receptors of endothelial cells and ligands on CTCs. Many CTCs express sialylated carbohydrate ligands on their surfaces that adhere t...

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Autors principals: Mitchell, Michael J., Chen, Christina S., Ponmudi, Varun, Hughes, Andrew D., King, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749772/
https://ncbi.nlm.nih.gov/pubmed/22421423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.02.018
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