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Knockdown of fucosyltransferase III disrupts the adhesion of circulating cancer cells to E-selectin without affecting hematopoietic cell adhesion

Adhesive interactions between selectins and their ligands play an essential role during cancer extravasation. Fucosylation of these proteins by fucosyltransferases, or FUTs, is critical for their functions. Using quantitative RT–PCR, we demonstrated that FUT4 and FUT7 are the predominant FUTs expres...

詳細記述

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書誌詳細
主要な著者: Yin, Xiaoyan, Rana, Kuldeepsinh, Ponmudi, Varun, King, Michael R.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995892/
https://ncbi.nlm.nih.gov/pubmed/20833389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2010.07.028
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