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Knockdown of fucosyltransferase III disrupts the adhesion of circulating cancer cells to E-selectin without affecting hematopoietic cell adhesion

Adhesive interactions between selectins and their ligands play an essential role during cancer extravasation. Fucosylation of these proteins by fucosyltransferases, or FUTs, is critical for their functions. Using quantitative RT–PCR, we demonstrated that FUT4 and FUT7 are the predominant FUTs expres...

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Bibliografski detalji
Glavni autori: Yin, Xiaoyan, Rana, Kuldeepsinh, Ponmudi, Varun, King, Michael R.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995892/
https://ncbi.nlm.nih.gov/pubmed/20833389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2010.07.028
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