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Fucosyltransferase VII improves the function of selectin ligands on cord blood hematopoietic stem cells

Selectins and their carbohydrate ligands mediate the homing of hematopoietic stem/progenitor cells (HSPCs) to the bone marrow. We have previously shown that ex vivo fucosylation of selectin ligands on HSPCs by α1,3 fucosyltransferase VI (FUT6) leads to improved human cord blood (CB)-HSPC engraftment...

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Detalhes bibliográficos
Main Authors: Wan, Xiang, Sato, Hidetaka, Miyaji, Hiromasa, McDaniel, J Michael, Wang, Yuesi, Kaneko, Etsuji, Gibson, BreeAnna, Mehta-D'Souza, Padmaja, Chen, Yiyuan, Dozmorov, Mikhail, Miller, Leonard P, Goodman, Jean, Sun, Zimin, Xia, Lijun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766281/
https://ncbi.nlm.nih.gov/pubmed/23899669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwt055
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