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Fucosyltransferase VII improves the function of selectin ligands on cord blood hematopoietic stem cells

Selectins and their carbohydrate ligands mediate the homing of hematopoietic stem/progenitor cells (HSPCs) to the bone marrow. We have previously shown that ex vivo fucosylation of selectin ligands on HSPCs by α1,3 fucosyltransferase VI (FUT6) leads to improved human cord blood (CB)-HSPC engraftment...

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Bibliographische Detailangaben
Hauptverfasser: Wan, Xiang, Sato, Hidetaka, Miyaji, Hiromasa, McDaniel, J Michael, Wang, Yuesi, Kaneko, Etsuji, Gibson, BreeAnna, Mehta-D'Souza, Padmaja, Chen, Yiyuan, Dozmorov, Mikhail, Miller, Leonard P, Goodman, Jean, Sun, Zimin, Xia, Lijun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766281/
https://ncbi.nlm.nih.gov/pubmed/23899669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwt055
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