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Differential regulation and impact of fucosyltransferase VII and core 2 β1,6-N-acetyl-glycosaminyltransferase for generation of E-selectin and P-selectin ligands in murine CD4(+) T cells

Ligands for E-selectin and P-selectin (E-lig and P-lig) are induced on CD4(+) T cells upon differentiation into effector T cells. Glycosyltransferases, especially α 1,3-fucosyltransferase VII (FucT-VII) and core 2 β1,6-N-acetyl-glycosaminyltransferase I (C2GlcNAcT-I), are critical for their synthesi...

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Detalhes bibliográficos
Main Authors: Schroeter, Micha F, Ratsch, Boris A, Lehmann, Jeanette, Baumgrass, Ria, Hamann, Alf, Syrbe, Uta
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530085/
https://ncbi.nlm.nih.gov/pubmed/23039181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12011
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