MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

Coronavirus (CoV) infections are commonly associated with respiratory and enteric disease in humans and animals. The 2003 outbreak of severe acute respiratory syndrome (SARS) highlighted the potentially lethal consequences of CoV-induced disease in humans. In 2012, a novel CoV (Middle East Respirato...

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Autors principals: de Wilde, Adriaan H., Raj, V. Stalin, Oudshoorn, Diede, Bestebroer, Theo M., van Nieuwkoop, Stefan, Limpens, Ronald W. A. L., Posthuma, Clara C., van der Meer, Yvonne, Bárcena, Montserrat, Haagmans, Bart L., Snijder, Eric J., van den Hoogen, Bernadette G.
Format: Artigo
Idioma:Inglês
Publicat: Society for General Microbiology 2013
Matèries:
Animal
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749523/
https://ncbi.nlm.nih.gov/pubmed/23620378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.052910-0
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