Cyclosporin A inhibits the replication of diverse coronaviruses

Low micromolar, non-cytotoxic concentrations of cyclosporin A (CsA) strongly affected the replication of severe acute respiratory syndrome coronavirus (SARS-CoV), human coronavirus 229E and mouse hepatitis virus in cell culture, as was evident from the strong inhibition of GFP reporter gene expressi...

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Bibliographic Details
Main Authors: de Wilde, Adriaan H., Zevenhoven-Dobbe, Jessika C., van der Meer, Yvonne, Thiel, Volker, Narayanan, Krishna, Makino, Shinji, Snijder, Eric J., van Hemert, Martijn J.
Format: Artigo
Language:Inglês
Published: Society for General Microbiology 2011
Subjects:
Animal
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352363/
https://ncbi.nlm.nih.gov/pubmed/21752960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.034983-0
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