Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture

Coronaviruses can cause respiratory and enteric disease in a wide variety of human and animal hosts. The 2003 outbreak of severe acute respiratory syndrome (SARS) first demonstrated the potentially lethal consequences of zoonotic coronavirus infections in humans. In 2012, a similar previously unknow...

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Hlavní autoři: de Wilde, Adriaan H., Jochmans, Dirk, Posthuma, Clara C., Zevenhoven-Dobbe, Jessika C., van Nieuwkoop, Stefan, Bestebroer, Theo M., van den Hoogen, Bernadette G., Neyts, Johan, Snijder, Eric J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136071/
https://ncbi.nlm.nih.gov/pubmed/24841269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03011-14
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