Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C

Enteroviruses (EVs) represent many important pathogens of humans. Unfortunately, no antiviral compounds currently exist to treat infections with these viruses. We screened the Prestwick Chemical Library, a library of approved drugs, for inhibitors of coxsackievirus B3, identified pirlindole as a pot...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Ulferts, Rachel, de Boer, S. Matthijn, van der Linden, Lonneke, Bauer, Lisa, Lyoo, Hey Rhyoung, Maté, Maria J., Lichière, Julie, Canard, Bruno, Lelieveld, Daphne, Omta, Wienand, Egan, David, Coutard, Bruno, van Kuppeveld, Frank J. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862474/
https://ncbi.nlm.nih.gov/pubmed/26856848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02182-15
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