Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C

Enteroviruses (EVs) represent many important pathogens of humans. Unfortunately, no antiviral compounds currently exist to treat infections with these viruses. We screened the Prestwick Chemical Library, a library of approved drugs, for inhibitors of coxsackievirus B3, identified pirlindole as a pot...

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Ulferts, Rachel, de Boer, S. Matthijn, van der Linden, Lonneke, Bauer, Lisa, Lyoo, Hey Rhyoung, Maté, Maria J., Lichière, Julie, Canard, Bruno, Lelieveld, Daphne, Omta, Wienand, Egan, David, Coutard, Bruno, van Kuppeveld, Frank J. M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Antiviral Agents
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862474/
https://ncbi.nlm.nih.gov/pubmed/26856848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02182-15
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