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Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C

Enteroviruses (EVs) represent many important pathogens of humans. Unfortunately, no antiviral compounds currently exist to treat infections with these viruses. We screened the Prestwick Chemical Library, a library of approved drugs, for inhibitors of coxsackievirus B3, identified pirlindole as a pot...

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Библиографические подробности
Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Ulferts, Rachel, de Boer, S. Matthijn, van der Linden, Lonneke, Bauer, Lisa, Lyoo, Hey Rhyoung, Maté, Maria J., Lichière, Julie, Canard, Bruno, Lelieveld, Daphne, Omta, Wienand, Egan, David, Coutard, Bruno, van Kuppeveld, Frank J. M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862474/
https://ncbi.nlm.nih.gov/pubmed/26856848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02182-15
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