Glutathione Reductase Is Essential for Host Defense against Bacterial Infection

Glutathione reductase (Gsr) catalyzes the reduction of glutathione disulfide to glutathione, a major cellular antioxidant. We have recently shown that Gsr is essential for host defense against the Gram-negative bacteria Escherichia coli in a mouse model of sepsis. While we have demonstrated that Gsr...

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Bibliographische Detailangaben
Hauptverfasser: Yan, Jing, Ralston, Melissa M., Meng, Xiaomei, Bongiovanni, Kathleen D., Jones, Amanda L., Benndorf, Rainer, Nelin, Leif D., Frazier, W. Joshua, Rogers, Lynette K., Smith, Charles V., Liu, Yusen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749296/
https://ncbi.nlm.nih.gov/pubmed/23623936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.04.015
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