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Glutathione Reductase Facilitates Host Defense by Sustaining Phagocytic Oxidative Burst and Promoting the Development of Neutrophil Extracellular Traps()

Glutathione reductase (Gsr)() catalyzes the reduction of glutathione disulfide to glutathione, which plays an important role in the bactericidal function of phagocytes. Since Gsr has been implicated in the oxidative burst in human neutrophils and is abundantly expressed in the lymphoid system, we hy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yan, Jing, Meng, Xiaomei, Wancket, Lyn M., Lintner, Katherine, Nelin, Leif D., Chen, Bernadette, Francis, Kevin P., Smith, Charles V., Rogers, Lynette K., Liu, Yusen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480216/
https://ncbi.nlm.nih.gov/pubmed/22279102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102683
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