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Glutathione Reductase Facilitates Host Defense by Sustaining Phagocytic Oxidative Burst and Promoting the Development of Neutrophil Extracellular Traps()

Glutathione reductase (Gsr)() catalyzes the reduction of glutathione disulfide to glutathione, which plays an important role in the bactericidal function of phagocytes. Since Gsr has been implicated in the oxidative burst in human neutrophils and is abundantly expressed in the lymphoid system, we hy...

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Bibliographic Details
Main Authors: Yan, Jing, Meng, Xiaomei, Wancket, Lyn M., Lintner, Katherine, Nelin, Leif D., Chen, Bernadette, Francis, Kevin P., Smith, Charles V., Rogers, Lynette K., Liu, Yusen
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480216/
https://ncbi.nlm.nih.gov/pubmed/22279102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102683
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