Glutathione Reductase Promotes Fungal Clearance and Suppresses Inflammation during Systemic Candida albicans Infection in Mice

Glutathione reductase (Gsr)() catalyzes the reduction of glutathione disulfide (GSSG) to glutathione (GSH), which plays an important role in redox regulation. We have previously shown that Gsr facilitates neutrophil bactericidal activities and is pivotal for host defense against bacterial pathogens....

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Veröffentlicht in:J Immunol
Hauptverfasser: Kim, Victoria Y., Batty, Abel, Li, Jinhui, Kirk, Sean G., Jin, Yi, Tang, Juan, Zhang, Jian, Rogers, Lynette K., Deng, Han-Xiang, Nelin, Leif D., Liu, Yusen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783371/
https://ncbi.nlm.nih.gov/pubmed/31501257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701686
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