Gene Therapy Model of X-linked Severe Combined Immunodeficiency Using a Modified Foamy Virus Vector

X-linked severe combined immunodeficiency (SCID-X1) is an inherited genetic immunodeficiency associated with mutations in the common cytokine receptor γ chain (γc) gene, and characterized by a complete defect of T and natural killer (NK) cells. Gene therapy for SCID-X1 using conventional retroviral...

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Main Authors: Horino, Satoshi, Uchiyama, Toru, So, Takanori, Nagashima, Hiroyuki, Sun, Shu-lan, Sato, Miki, Asao, Atsuko, Haji, Yoichi, Sasahara, Yoji, Candotti, Fabio, Tsuchiya, Shigeru, Kure, Shigeo, Sugamura, Kazuo, Ishii, Naoto
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749225/
https://ncbi.nlm.nih.gov/pubmed/23990961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071594
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