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Foamy Virus Vector-mediated Gene Correction of a Mouse Model of Wiskott–Aldrich Syndrome

The Wiskott–Aldrich syndrome (WAS) is an X-linked disorder characterized by eczema, thrombocytopenia and immunodeficiency. Hematopoietic cell transplantation can cure the disease and gene therapy is being tested as an alternative treatment option. In this study, we assessed the use of foamy virus (F...

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Detalhes bibliográficos
Main Authors: Uchiyama, Toru, Adriani, Marsilio, Jagadeesh, G Jayashree, Paine, Adam, Candotti, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369282/
https://ncbi.nlm.nih.gov/pubmed/22215016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.282
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