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Foamy Virus Vector-mediated Gene Correction of a Mouse Model of Wiskott–Aldrich Syndrome

The Wiskott–Aldrich syndrome (WAS) is an X-linked disorder characterized by eczema, thrombocytopenia and immunodeficiency. Hematopoietic cell transplantation can cure the disease and gene therapy is being tested as an alternative treatment option. In this study, we assessed the use of foamy virus (F...

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Bibliographische Detailangaben
Hauptverfasser: Uchiyama, Toru, Adriani, Marsilio, Jagadeesh, G Jayashree, Paine, Adam, Candotti, Fabio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369282/
https://ncbi.nlm.nih.gov/pubmed/22215016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.282
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