Development of a Multi-Step Leukemogenesis Model of MLL-Rearranged Leukemia Using Humanized Mice

Mixed-lineage-leukemia (MLL) fusion oncogenes are intimately involved in acute leukemia and secondary therapy-related acute leukemia. To understand MLL-rearranged leukemia, several murine models for this disease have been established. However, the mouse leukemia derived from mouse hematopoietic stem...

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Detalhes bibliográficos
Main Authors: Moriya, Kunihiko, Suzuki, Makiko, Watanabe, Yohei, Takahashi, Takeshi, Aoki, Yoko, Uchiyama, Toru, Kumaki, Satoru, Sasahara, Yoji, Minegishi, Masayoshi, Kure, Shigeo, Tsuchiya, Shigeru, Sugamura, Kazuo, Ishii, Naoto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380045/
https://ncbi.nlm.nih.gov/pubmed/22745659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037892
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