טוען...
The length of the calmodulin linker determines the extent of transient interdomain association and target affinity
Calmodulin (CaM), the prototypical calcium sensing protein in eukaryotes, comprises two domains separated by a short flexible linker, which allows CaM to assume a wide range of extended and compact conformations. Here we use NMR relaxation measurements to explore the role of the linker in CaM functi...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3748814/ https://ncbi.nlm.nih.gov/pubmed/23782151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4051422 |
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