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Interdomain Linkers of Homologous Response Regulators Determine Their Mechanism of Action

OmpR and PhoB are response regulators that contain an N-terminal phosphorylation domain and a C-terminal DNA binding effector domain connected by a flexible interdomain linker. Phosphorylation of the N terminus results in an increase in affinity for specific DNA and the subsequent regulation of gene...

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Detalhes bibliográficos
Main Authors: Walthers, Don, Tran, Van K., Kenney, Linda J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC141822/
https://ncbi.nlm.nih.gov/pubmed/12486069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.1.317-324.2003
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