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Tyrosine kinase inhibition facilitates autophagic SNCA/α-synuclein clearance
The effects of ABL1/ABL inhibition on clearance of SNCA/α-synuclein were evaluated in animal models of α-synucleinopathies. Parkinson disease (PD) is a movement disorder characterized by death of dopaminergic substantia nigra (SN) neurons and brain accumulation of SNCA. The tyrosine kinase ABL1 is a...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Landes Bioscience
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3748197/ https://ncbi.nlm.nih.gov/pubmed/23787811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.25368 |
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