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Theoretical Insights into Catalytic Mechanism of Protein Arginine Methyltransferase 1
Protein arginine methyltransferase 1 (PRMT1), the major arginine asymmetric dimethylation enzyme in mammals, is emerging as a potential drug target for cancer and cardiovascular disease. Understanding the catalytic mechanism of PRMT1 will facilitate inhibitor design. However, detailed mechanisms of...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3748068/ https://ncbi.nlm.nih.gov/pubmed/23977297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072424 |
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