Catalytic Mechanism Investigation of Lysine-Specific Demethylase 1 (LSD1): A Computational Study

Lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, is a flavin-dependent amine oxidase which specifically demethylates mono- or dimethylated H3K4 and H3K9 via a redox process. It participates in a broad spectrum of biological processes and is of high importance in cell p...

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Detalhes bibliográficos
Main Authors: Kong, Xiangqian, Ouyang, Sisheng, Liang, Zhongjie, Lu, Junyan, Chen, Liang, Shen, Bairong, Li, Donghai, Zheng, Mingyue, Li, Keqin Kathy, Luo, Cheng, Jiang, Hualiang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184146/
https://ncbi.nlm.nih.gov/pubmed/21984927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025444
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