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Catalytic Mechanism Investigation of Lysine-Specific Demethylase 1 (LSD1): A Computational Study
Lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, is a flavin-dependent amine oxidase which specifically demethylates mono- or dimethylated H3K4 and H3K9 via a redox process. It participates in a broad spectrum of biological processes and is of high importance in cell p...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3184146/ https://ncbi.nlm.nih.gov/pubmed/21984927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025444 |
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