Pulmonary Hypertension Secondary to Left-heart Failure Involves Peroxynitrite-induced Downregulation of PTEN in the Lung

Pulmonary hypertension (PH) that occurs after left-heart failure (LHF), classified as Group 2 PH, involves progressive pulmonary vascular remodeling induced by smooth muscle cell (SMC) proliferation. However, mechanisms involved in the activation of SMCs remain unknown. The objective of this study w...

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Bibliografiske detaljer
Main Authors: Ravi, Yazhini, Selvendiran, Karuppaiyah, Naidu, Shan K., Meduru, Sarath, Citro, Lucas A., Bognár, Balázs, Khan, Mahmood, Kálai, Tamás, Hideg, Kálmán, Kuppusamy, Periannan, Sai-Sudhakar, Chittoor B.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747571/
https://ncbi.nlm.nih.gov/pubmed/23339168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00514
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