Pharmacokinetics and Pharmacodynamics of Recombinant Human EPO-Fc Fusion Protein In Vivo

In this study, the in vivo pharmacokinetics and pharmacodynamics of a novel recombinant human erythropoietin (rhEPO) Fc fusion protein, rhEPO-Fc, were studied in both rodents and rhesus monkeys. Animal models of anemia induced by irradiation, cyclophosphamide and partial renal ablation were used to...

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Main Authors: Shi, Xunlong, Yang, Jianjun, Zhu, Haiyan, Ye, Li, Feng, Meiqing, Li, Jiyang, Huang, Hai, Tao, Qun, Ye, Dan, Sun, Lee-Hwei K., Sun, Bill N. C., Sun, Cecily R. Y., Han, Guizhen, Liu, Yuanyuan, Yao, Minghui, Zhou, Pei, Ju, Dianwen
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747110/
https://ncbi.nlm.nih.gov/pubmed/23977338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072673
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