Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling

The inhibitory reversible oxidation of protein tyrosine phosphatases (PTPs) is an important regulatory mechanism in growth factor signaling. Studies on PTP oxidation have focused on pathways that increase or decrease reactive oxygen species levels and thereby affect PTP oxidation. The processes invo...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Dagnell, Markus, Frijhoff, Jeroen, Pader, Irina, Augsten, Martin, Boivin, Benoit, Xu, Jianqiang, Mandal, Pankaj K., Tonks, Nicholas K., Hellberg, Carina, Conrad, Marcus, Arnér, Elias S. J., Östman, Arne
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746926/
https://ncbi.nlm.nih.gov/pubmed/23901112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302891110
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi