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Reactivation of oxidized PTP1B and PTEN by Thioredoxin 1
The transient inactivation of protein phosphatases contributes to the efficiency and temporal control of kinase-dependent signal transduction. In particular, members of the protein tyrosine phosphatase family are known to undergo reversible oxidation of their active site cysteine. The thiol oxidatio...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4162488/ https://ncbi.nlm.nih.gov/pubmed/24976139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12898 |
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