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Bispecific antibodies directed to CD4 domain 2 and HIV envelope exhibit exceptional breadth and picomolar potency against HIV-1

In the absence of an effective HIV-1 vaccine, passive immunization using broadly neutralizing Abs or Ab-like molecules could provide an alternative to the daily administration of oral antiretroviral agents that has recently shown promise as preexposure prophylaxis. Currently, no single broadly neutr...

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Detalhes bibliográficos
Main Authors: Pace, Craig S., Song, Ruijiang, Ochsenbauer, Christina, Andrews, Chasity D., Franco, David, Yu, Jian, Oren, Deena A., Seaman, Michael S., Ho, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746901/
https://ncbi.nlm.nih.gov/pubmed/23878231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304985110
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