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Highly Complementary Target RNAs Promote Release of Guide RNAs from Human Argonaute2
Argonaute proteins use small RNAs to guide the silencing of complementary target RNAs in many eukaryotes. Although small RNA biogenesis pathways are well studied, mechanisms for removal of guide RNAs from Argonaute are poorly understood. Here we show that the Argonaute2 (Ago2) guide RNA complex is e...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3746828/ https://ncbi.nlm.nih.gov/pubmed/23664376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.04.001 |
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