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Tat-PTD-Modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy

Secretogranin III (SGC3) belongs to the granin family and is highly expressed in endocrine and neural tissues. The human SCG3 promoter has not yet been characterized. We identified that a 0.5-kb DNA fragment upstream of the SCG3 gene can selectively drive transgene expression in neuroblastoma cell l...

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Autors principals: Jin, Chuan, Yu, Di, Čančer, Matko, Nilsson, Berith, Leja, Justyna, Essand, Magnus
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746216/
https://ncbi.nlm.nih.gov/pubmed/23889332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.132
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