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Intragenic epigenetic changes modulate NCAM alternative splicing in neuronal differentiation
Alternative splicing contributes to cell type-specific transcriptomes. Here, we show that changes in intragenic chromatin marks affect NCAM (neural cell adhesion molecule) exon 18 (E18) alternative splicing during neuronal differentiation. An increase in the repressive marks H3K9me2 and H3K27me3 alo...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
European Molecular Biology Organization
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3746202/ https://ncbi.nlm.nih.gov/pubmed/23892457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.167 |
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