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Neuronal cell depolarization induces intragenic chromatin modifications affecting NCAM alternative splicing

In search for physiological pathways affecting alternative splicing through its kinetic coupling with transcription, we found that membrane depolarization of neuronal cells triggers the skipping of exon 18 from the neural cell adhesion molecule (NCAM) mRNA, independently of the calcium/calmodulin pr...

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Autors principals: Schor, Ignacio E., Rascovan, Nicolás, Pelisch, Federico, Alló, Mariano, Kornblihtt, Alberto R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657401/
https://ncbi.nlm.nih.gov/pubmed/19251664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810666106
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