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Epigenetics at the base of alternative splicing changes that promote colorectal cancer

Chromatin modification influences gene expression by either repressing or activating genes, depending on the specific histone mark. Chromatin structure can also influence alternative splicing of transcripts; however, the mechanisms by which epigenetic marks influence splicing are poorly understood....

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autor principal: Kornblihtt, Alberto R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669579/
https://ncbi.nlm.nih.gov/pubmed/28825597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96497
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