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Epigenetics at the base of alternative splicing changes that promote colorectal cancer

Chromatin modification influences gene expression by either repressing or activating genes, depending on the specific histone mark. Chromatin structure can also influence alternative splicing of transcripts; however, the mechanisms by which epigenetic marks influence splicing are poorly understood....

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awdur: Kornblihtt, Alberto R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669579/
https://ncbi.nlm.nih.gov/pubmed/28825597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96497
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