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Epigenetics at the base of alternative splicing changes that promote colorectal cancer

Chromatin modification influences gene expression by either repressing or activating genes, depending on the specific histone mark. Chromatin structure can also influence alternative splicing of transcripts; however, the mechanisms by which epigenetic marks influence splicing are poorly understood....

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Bibliografske podrobnosti
izdano v:J Clin Invest
Glavni avtor: Kornblihtt, Alberto R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669579/
https://ncbi.nlm.nih.gov/pubmed/28825597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96497
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