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Sequence Selective Recognition of Double-Stranded RNA at Physiologically Relevant Conditions Using PNA-Peptide Conjugates

Conjugation of short peptide nucleic acids (PNA) with tetralysine peptides strongly enhanced triple helical binding to RNA at physiologically relevant conditions. The PNA hexamers and heptamers carrying cationic nucleobase and tetralysine modifications displayed high binding affinity for complementa...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Muse, Oluwatoyosi, Zengeya, Thomas, Mwaura, Juddy, Hnedzko, Dziyana, McGee, Dennis W., Grewer, Christof T., Rozners, Eriks
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745792/
https://ncbi.nlm.nih.gov/pubmed/23721369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400144x
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