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Oskar Is Targeted for Degradation by the Sequential Action of Par-1, GSK-3, and the SCF(-Slimb) Ubiquitin Ligase
Translation of oskar messenger RNA (mRNA) is activated at the posterior of the Drosophila oocyte, producing Long Oskar, which anchors the RNA, and Short Oskar, which nucleates the pole plasm, containing the posterior and germline determinants. Here, we show that Oskar is phosphorylated by Par-1 and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3744808/ https://ncbi.nlm.nih.gov/pubmed/23948254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.06.011 |
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